For vaccination of healthy cattle 3 months of age and older to help prevent respiratory disease caused by IBR BVD Type 2 and BRSV and to aid in the control of disease caused by BVD Type 1 PI3 Mannheimia haemolytica and Pasteurella multocida. Provides immunity for at least one year against IBR and BVD Types 1 and 2 and at least 16 weeks against Mannheimia haemolytica and Pasteurella multocida. Also indicated for healthy cows and heifers prior to breeding to help prevent fetal infection and persistently infected calves caused by BVD Types 1 and 2 and to help reduce abortion associated with IBR.